Amodiaquine

Basic Information

Place of Origin : India
Minimum Order Quantity : Negotiation
Price : Negotiation
Delivery Time : Negotiation
Payment Terms : D/P , D/A , B/L , T/T
Packaging Details : Your demand
Supply Ability : Negotiation
COA : Available
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  • Detail Information
  • Product Description

Amodiaquine API

Cas No :

6398-98-7
Name :

Amodiaquine
Synonyms :

4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)methyl]phenol
Molecular Formula :

C20H22ClN3O
Melting Point :

150-160°C
Boiling Point :

478.0±45.0 °C at 760 mmHg
Molecular Weight :

355.861 g/mol
Density :

1.3±0.1 g/cm3
Solubility :

Soluble in water, sparingly soluble in alcohol, and very slightly soluble in benzene, chloroform, and ether.

Uses :


  • Amodiaquine is an aminoquinoline used for the therapy of malaria. Amodiaquine has been linked to severe cases of acute hepatitis which can be fatal, for which reason it is recommended for use only as treatment and not for prophylaxis against malaria.

Amodiaquine API

Like other quinoline derivatives, it is thought to inhibit heme polymerase activity. This results in accumulation of free heme, which is toxic to the parasites. The drug binds the free heme preventing the parasite from converting it to a form less toxic. This drug-heme complex is toxic and disrupts membrane function.

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