Cinnarizine

Basic Information

Place of Origin : India
Minimum Order Quantity : Negotiation
Price : Negotiation
Delivery Time : Negotiation
Payment Terms : D/P , D/A , B/L , T/T
Packaging Details : Your demand
Supply Ability : Negotiation
COA : Available
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  • Detail Information
  • Product Description

Cinnarizine API

Cas No :

298-57-7
Name :

Cinnarizine
Synonyms :

(E)-1-(Diphenylmethyl)-4-(3-phenylprop-2-enyl)piperazine
Molecular Formula :

C26H28N2
Melting Point :

117-120°C
Boiling Point :

509.2±38.0 °C at 760 mmHg
Molecular Weight :

368.514 g/mol
Density :

1.1±0.1 g/cm3
Solubility :

It is a weak base with poor aqueous solubility. According to a paper the solubility of cinnarizine is highly pH dependent, that is, 0.29 mg/mL at pH 2, 0.017 mg/mL at pH 5, and 0.002 mg/mL at high pH of 6.5

Uses :


  • Antihistamine used for travel sickness and vertigo - NHS.

CinnarizineAPI

Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood.

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