Flurbiprofen

Basic Information

Place of Origin : India
Minimum Order Quantity : Negotiation
Price : Negotiation
Delivery Time : Negotiation
Payment Terms : D/P , D/A , B/L , T/T
Packaging Details : Your demand
Supply Ability : Negotiation
COA : Available
Contact Now     Chat Now
  • Detail Information
  • Product Description

Flurbiprofen API

Cas No :

5104-49-4
Name :

Flurbiprofen
Synonyms :

2-(3-fluoro-4-phenylphenyl)propanoic acid
Molecular Formula :

C15H13FO2
Melting Point :

117 °C
Boiling Point :

376.2 °C
Molecular Weight :

244.261 g/mol
Density :

1.2±0.1 g/cm3
Solubility :

Flurbiprofen is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide (DMF), which should be purged with an inert gas. The solubility of flurbiprofen in ethanol and DMF is approximately 25 mg/ml, and approximately 10 mg/ml in DMSO.

Uses :


  • Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve symptoms of arthritis (osteoarthritis and rheumatoid arthritis), such as inflammation, swelling, stiffness, and joint pain.

Flurbiprofen API

Similar to other NSAIAs, the anti-inflammatory effect of flurbiprofen occurs via reversible inhibition of cyclooxygenase (COX), the enzyme responsible for the conversion of arachidonic acid to prostaglandin G2 (PGG2) and PGG2 to prostaglandin H2 (PGH2) in the prostaglandin synthesis pathway. This effectively decreases the concentration of prostaglandins involved in inflammation, pain, swelling and fever. Flurbiprofen is a non-selective COX inhibitor and inhibits the activity of both COX-1 and -2. It is also one of the most potent NSAIAs in terms of prostaglandin inhibitory activity.

×