Glibenclamide – Glyburide

Basic Information

Place of Origin : India
Minimum Order Quantity : Negotiation
Price : Negotiation
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Payment Terms : D/P , D/A , B/L , T/T
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  • Product Description

Glibenclamide - Glyburide API

Cas No :

10238-21-8
Name :

Glibenclamide – Glyburide
Synonyms :

5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)
phenyl]ethyl]-2-methoxybenzamide
Molecular Formula :

C23H28ClN3O5S
Melting Point :

169 to 170 °C
Boiling Point :

209-214 °C

Molecular Weight :

494.004 g/mol
Density :

1.4±0.1 g/cm3
Solubility :

Glibenclamide is virtually insoluble in water and ether; it is soluble in 330 parts of alcohol, in 36 parts of chloroform, and in 250 parts of methanol.

Uses :


  • ​Glibenclamide is used to manage diabetes. It helps the pancreas to release more insulin to bring your blood sugar levels down.

Glibenclamide - Glyburide API

The mechanism of action of the drug consists in the inhibition of the ATP-sensitive K+ channels, which leads to depolarization of the cells and insulin secretion. Based on the same mechanism are also the extrapancreatic action of the drug at the liver, skeletal muscle, heart muscle and smooth muscle sites.

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