Lornoxicam

Basic Information

Place of Origin : India
Minimum Order Quantity : Negotiation
Price : Negotiation
Delivery Time : Negotiation
Payment Terms : D/P , D/A , B/L , T/T
Packaging Details : Your demand
Supply Ability : Negotiation
COA : Available
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  • Detail Information
  • Product Description

Lornoxicam API

Cas No :

70374-39-9
Name :

Lornoxicam
Synonyms :

(3E)-6-chloro-3-[hydroxy(pyridin-2-ylamino)methylene]-2-methyl-2,3-dihydro-4H-thieno[2,3-e][1,2]thiazin-4-one 1,1-dioxide
Molecular Formula :

C13H10ClN3O4S2
Melting Point :

225-230°C
Boiling Point :

N/A
Molecular Weight :

371.8192 g/mol
Density :

1.742±0.06 g/cm3
Solubility :

In ethanol and DMF is approximately 1 mg/ml and approximately 2 mg/ml in DMSO. It is also soluble in water at a concentration of 1 mg/ml.

Uses :


  • Lornoxicam is a non‐steroidal anti‐inflammatory drug (NSAID) that is used as a painkiller (analgesic). A high level of pain relief is experienced by about 45% of those with moderate to severe postoperative dental pain after a single dose of lornoxicam 8 mg, compared to about 10% with placebo.

Lornoxicam API

Lornoxicam, a COX-1 and COX-2 inhibitor, is a new nonsteroidal anti-inflammatory drug (NSAID).Target: COXLornoxicam showed a balanced inhibition of COX-1/-2 exhibiting the lowest IC50 (0.005 microM/0.008 microM) of the large panel of NSAIDs tested. lornoxicam showed a marked inhibition of IL-6 formation (IC50 54 microM) while the formation ofTNF-alpha, IL-1beta and IL-8 was only moderately affected. Lornoxicam is effective in the treatment of patients with activated osteoarthritis; the analgesic and anti-inflammatory effects of lornoxicam are significantly superior to those of rofecoxib without inferiority in tolerability. Lornoxicam was fully effective for prevention of hyperalgesia.

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