Losartan

Basic Information

Place of Origin : India
Minimum Order Quantity : Negotiation
Price : Negotiation
Delivery Time : Negotiation
Payment Terms : D/P , D/A , B/L , T/T
Packaging Details : Your demand
Supply Ability : Negotiation
COA : Available
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  • Detail Information
  • Product Description

Losartan API

Cas No :

114798-26-4
Name :

Losartan
Synonyms :

114798-26-4
DUP 89
allisartan
Lortaan
Molecular Formula :

C22H23ClN6O
Melting Point :

184 °C
Boiling Point :

682 °C
Molecular Weight :

422.91 g/mol
Density :

N/A
Solubility :

Freely soluble in water; soluble in alcohols; slightly soluble in common organic solvents, such as acetonitrile, methyl ethyl ketone.

Uses :


  • Losartan is used alone or in combination with other medications to treat high blood pressure. Losartan is also used to decrease the risk of stroke in people who have high blood pressure and a heart condition called left ventricular hypertrophy (enlargement of the walls of the left side of the heart).

Losartan API

Losartan is a non-peptide angiotensin II antagonist with antihypertensive activity. Upon administration, losartan and its active metabolite selectively and competitively blocks the binding of angiotensin II to the angiotensin I (AT1) receptor. This blocks the vasoconstricting and aldosterone-secreting actions of angiotensin II, leading to a decrease in blood pressure. Angiotensin II, formed from angiotensin I by angiotensin-converting enzyme (ACE), stimulates the adrenal cortex to synthesize and secrete aldosterone, which decreases the excretion of sodium and increases the excretion of potassium. Angiotensin II also acts as a vasoconstrictor in vascular smooth muscle.

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