Phenylbutazone

Basic Information

Place of Origin : India
Minimum Order Quantity : Negotiation
Price : Negotiation
Delivery Time : Negotiation
Payment Terms : D/P , D/A , B/L , T/T
Packaging Details : Your demand
Supply Ability : Negotiation
COA : Available
  • Detail Information
  • Product Description

Phenylbutazone API

Cas No :

50-33-9

Name :

Phenylbutazone

Synonyms :

4-Butyl-1,2-diphenyl-pyrazolidine-3,5-dione

Molecular Formula :

C19H20N2O2

Melting Point :

106-108 °C

Boiling Point :

448.76°C

Molecular Weight :

308.374 g/mol

Density :

1.2±0.1 g/cm3

Solubility :

Phenylbutazone is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide (DMF). The solubility of phenylbutazone is approximately 50 mg/ml in ethanol and approximately 25 mg/ml in DMSO and DMF.

Uses :


  • Phenylbutazone, often referred to as "bute,"is a nonsteroidal anti-inflammatory, antipyretic, and analgesic drug (NSAID) for the short-term treatment of pain and fever results from rheumatoid arthritis, ankylosing spondylitis, gouty arthritis, and osteoarthritis. Phenylbutazone has been removed from the United States market due to the availability of newer drugs with less adverse effects. Phenylbutazone is a nonsteroidal anti-inflammatory drug (NSAID) effective in treating fever, pain, and inflammation in the body. As a group, NSAIDs are non-narcotic relievers of mild to moderate pain of many causes, including injury, menstrual cramps, arthritis and other musculoskeletal conditions.

Phenylbutazone API

Recent studies have found that the generating mechanism from phenylbutazone anti-inflammatory, analgesic and anti-rheumatic effect is not due to pituitary-adrenal excitement may be due to drugs that inhibit the generation of inflammatory tissue inflammation related active substances, such as synthesis of prostaglandins, white blood cells activities and transfer, release and activity of lysosomal enzymes; pain may also inhibit prostaglandin synthesis results.

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