Pyrimethamine API
| Cas No : | 58-14-0 |
|---|---|
| Name : | Pyrimethamine |
| Synonyms : | 5-(4-chlorophenyl)-6-ethyl- 2,4-pyrimidinediamine |
| Molecular Formula : | C12H13ClN4 |
| Melting Point : | 233.5 °C |
| Boiling Point : | 368.4±52.0 °C at 760 mmHg |
| Molecular Weight : | 248.71 g·mol−1 |
| Density : | 1.4±0.1 g/cm3 |
| Solubility : | Pyrimethamine is sparingly soluble in aqueous buffers. For maximum solubility in aqueous buffers, pyrimethamine should first be dissolved in DMSO and then diluted with the aqueous buffer of choice. Pyrimethamine has a solubility of approximately 0.5 mg/ml in a 1:1 solution of DMSO:PBS (pH 7.2) using this method. |
Uses :
- Pyrimethamine is an antiparasitic prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of Toxoplasma gondii infection (toxoplasmosis). Pyrimethamine is usually used together with a sulfonamide (sulfa medicine) to treat toxoplasmosis.
