Simvastatin

Basic Information

Place of Origin : India
Minimum Order Quantity : Negotiation
Price : Negotiation
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Payment Terms : D/P , D/A , B/L , T/T
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  • Detail Information
  • Product Description

Simvastatin API

Cas No :

79902-63-9
Name :

Simvastatin
Synonyms :

(1s-(1-alpha,3-dro-4-hydroxy-6-oxo-2h-pyran-2-yl)ethyl)-1-naphthalenyleste
Molecular Formula :

C25H38O5
Melting Point :

139°C
Boiling Point :

564.9±50.0°C
Molecular Weight :

418.57
Density :

1.11±0.1 G/cm3
Solubility :

DMSO: ≥20mg/mL

Uses :


  • Reductase inhibitor, can reduce the concentration of serum total cholestol, inhibit cholesterol synthesis. It is used for the treatment of primary hypercholesterolemia whose cholesterol level exceeds 7.8mmol/L and other treatments are ineffective or cannot be tolerated.

Simvastatin API

Simvastatin is a statins type of lipid lowering drug and is a synthetic derivative of Aspergillus tumefaciens fermentation products, which is used to control the cholesterol content in blood and prevent cardiovascular disease. Simvastatin is a reductase inhibitor of HMG CoA, which inhibits the synthesis of endogenous derived cholesterol, and is a lipid regulator. It can reduce the cholesterol (TC) content in serum, liver and aorta of hyperlipidemia rabbits, and the level of VLDL-C and LDL-C.

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