Voriconazole

Basic Information

Place of Origin : India
Minimum Order Quantity : Negotiation
Price : Negotiation
Delivery Time : Negotiation
Payment Terms : D/P , D/A , B/L , T/T
Packaging Details : Your demand
Supply Ability : Negotiation
COA : Available
Contact Now     Chat Now
  • Detail Information
  • Product Description

Voriconazole API

Cas No :

137234-62-9
Name :

Voriconazole
Synonyms :

(2R,3S)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
Molecular Formula :

C16H14F3N5O
Melting Point :

129-134°C
Boiling Point :

508.6 °C at 760 mmHg
Molecular Weight :

349.317 g/mol
Density :

1.4±0.1 g/cm3
Solubility :

Low aqueous solubility, its maximum solubility being in acidic conditions (2.7 mg/ml at pH 1.2).

Uses :


  • Voriconazole is used to treat serious fungal or yeast infections, such as aspergillosis (fungal infection in the lungs), candidemia (fungal infection in the blood), esophageal candidiasis (candida esophagitis), or other fungal infections (infections in the skin, stomach, kidney, bladder, or wounds).

Voriconazole API

The mechanism of action of voriconazole, similar to that of all azole agents, is inhibition of cytochrome P450 (CYP 450)–dependent 14α-lanosterol demethylation, which is a vital step in cell membrane ergosterol synthesis by fungi [1]. For yeasts, voriconazole appears to be fungistatic, as are other azoles.

×